Starting the Game:
Once you have connected and exchanged pleasantries (talking to your opponent is done simply by typing, your text will automatically appear in the text box), you're ready to play. Deciding who goes first is most often done by way of coin flip. One person calls 'Heads' or 'Tails', and the other flips the coin. Flipping the coin can be done by pressing Ctrl-F, or selecting 'Flip a Coin' from the Action menu. After the flip, you may need to give control of the current turn to your opponent if he chooses to play first. This is done by pressing the "End Turn" button, or selecting 'It is Opponent's Turn' from the Game menu.
Now that you've determined who will play first, you'll need to draw your opening hand of 7 cards. You can either click on the Draw Card button to draw a card, hold shift and click the Draw Card button and enter the number of cards you wish to draw, or press Ctrl-D to draw a card.